p16ink4a基因,p16ink4a gene
1)p16ink4a genep16ink4a基因
1.p16INK4a gene extron 1 and extron 2 inactivation wa.方法:对20例皮肤鳞状细胞癌、24例基底细胞癌、18例Bowen病、12例光线性角化病以及8例脂溢性角化病共计82例患者中具不同增生行为的KC,分别应用免疫组化检测其p16INK4a蛋白表达;应用聚合酶链反应(PCR)、PCR-单链构象多态性以及PCR-限制性内切酶分析方法分别检测p16INK4a基因外显子1和外显子2的缺失、突变和甲基化。
2.Objective To explore the dynamic expression of p16INK4a gene in lung fibroblasts of neonatal rats with chronic lung disease(CLD).目的探讨p16INK4a基因在高氧致慢性肺疾病(CLD)新生鼠肺成纤维细胞中的动态表达。
2)p16 INK4ap16INK4a
1.Objective This study was to investigate the expression meaning of hMSH2 andp16 INK4a in gastric cancer.目的探讨错配修复基因hMSH2和抑癌基因p16INK4a在胃癌组织中表达的意义。
2.Objective To investigate the expression of P16 INK4a and CyclinD1 in endometrial carcinoma and their clinical significance,and to assess the correlation between their expression status.目的研究P16INK4a和CyclinD1 在子宫内膜癌中的表达及临床意义, 并探讨两者表达的相关性。
3.Objective To study the expressions of p14 ARF andp16 INK4a proteins in small cell lung cancer (SCLC) and the clinical significance.目的研究p14 ARF、p16INK4a蛋白在小细胞肺癌 (smallcelllungcancer ,SCLC)中的表达及其临床意义。
p16 INK4ap16INK4a
1.Objective This study was to investigate the expression meaning of hMSH2 andp16 INK4a in gastric cancer.目的探讨错配修复基因hMSH2和抑癌基因p16INK4a在胃癌组织中表达的意义。
2.Objective To investigate the expression of P16 INK4a and CyclinD1 in endometrial carcinoma and their clinical significance,and to assess the correlation between their expression status.目的研究P16INK4a和CyclinD1 在子宫内膜癌中的表达及临床意义, 并探讨两者表达的相关性。
3.Objective To study the expressions of p14 ARF andp16 INK4a proteins in small cell lung cancer (SCLC) and the clinical significance.目的研究p14 ARF、p16INK4a蛋白在小细胞肺癌 (smallcelllungcancer ,SCLC)中的表达及其临床意义。
3)P16~(INK4A)P16INK4A
1.Objective To investigate the relationship between HPV infection and the expression of P16~(INK4A) in cervical intraepithelial neoplasia(CIN) and cervical squamous cell carcinomas(SCC).目的探讨HPV(16/18型)感染和P16INK4A蛋白表达在人类宫颈鳞癌(SCC)及其癌前病变(CIN)中的关系。
2.Objective To explore the clinicopathologic significance of the different subtype of HPV,p16~(INK4A),p53,Ki-67 and ER expression in the diseased cervical tissues with different degree of severity.目的探讨人乳头状瘤病毒的不同亚型及p16INK4Ap53、Ki-67、ER在不同程度宫颈鳞状上皮病变中的表达及临床病理意义。
3.Objective To compare the expressions of p16~(ink4a) and Ki-67 in human cervical lesions.目的对p16ink4a与Ki-67作为辅助诊断人宫颈病变的两种标记物进行比较。
4)p16INK4a proteinp16INK4a蛋白
1.Objective To discuss the expression ofp16INK4a protein and its clinical pathological characteristics in the CINs and invasive carcinoma of the cervix.目的研究p16INK4a蛋白表达在宫颈浸润癌前病变(CIN)和宫颈浸润癌组织中的意义。
2.Objective: To elucidate thep16INK4a protein expression and gene inactivation mechanism in human keratinocytic tumors.目的:探讨角质形成细胞(KC)增生行为与p16INK4a蛋白表达及其基因失活的相关性。
5)p16INK4A/p16p16INK4A/p16蛋白
6)gene[英][d?i:n][美][d?in]基因
1.Study of the Preparation and the Characteristics of pRc/CMV-BChE Gene-chitosan nanoparticles ①;丁酰胆碱酯酶基因-壳聚糖纳米粒初步研究
2.Correlation between traditional Chinese medicine syndromes in primary immunoglobulin A nephropathy and A267G in 5"-untranslated region within exonal of megsingene;Megsin基因E1-5’UTR区A267G与免疫球蛋白A型肾病阴虚证的相关性
3.Study ongene chip of leiomyoma of uterus;子宫肌瘤基因芯片的研究
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